Occupational Asthma and Rhinitis Caused by Urea Formaldehyde?

CommunIcations to the Editor genesis ofthe pulmonary edema in this patient. Indeed, endorphins are released in stress situations and they can adversely affect physiologic systems, such as respiration and circulation.’ In the human fetus at term, plasma levels of beta-endorphins and betaLPH are inversely correlated with arterial pH and Po5 suggesting that hypoxia and secondary acidosis may be important stimuli controlling the release of these peptides.2 Recently, Bar.or et al3 reported a dramatic clinical improvement after naloxone therapy in a patient with high-altitude pulmonary edema. The finding ofa high plasma beta-endorphin concentration in this patient suggested that endorphins may play a role in this disorder. Development of pulmonaryedemain animals byselectivecerebralperfusion with the hypoxemic blood as observed by Moss et a14 might be explained in part by endorphinergic mechanisms. Interestingly, endogenous oploids might also play a role in the pathogenesis of apnea.5